The Oral Health or preventive dental materials include pit and fissure sealants, restorative materials (compomers, glass ionomer cement), toothpaste, gels, mouthwashes, liners, and bases. Some of these dental materials physically prevent the occurrence or progress of the dental disease by modifying the anatomy of favorable sites for microbial growth such as deep pit and fissures. While other materials release therapeutic or preventive agents such as fluoride or chlorhexidine that prevent and inhibit the progress of the disease.